Quinze dias by Vitor Martins6/27/2023 Respiratory failure, cytokine storm, thromboembolic phenomena and acute fulminant myocarditis are the predominant known causes of death 12, 13, 14 with a 1.2-7.7% case-fatality rate worldwide to date. 7, 8, 9, 10, 11 With growing knowledge about the disease, other clinical symptoms are constantly being reported. 4, 5, 6 COVID-19 disease presents with a wide range of symptoms but predominantly as an acute respiratory disease and fever 7 leading to hospitalization in about 10-15% of patients and critical intensive care (ICU) in 3-14.2% of patients. However, numbers may be in fact higher due to the virus being highly infectious and asymptomatic patients being capable of transmission. The virus led to a pandemic, with more than 53.1 million reported infections and 1.3 million deaths 3 to date. In December 2019, an increasing number of cases of patients with pneumonia of unknown origin was detected in the Hubei province in China, 1, 2 and SARS-CoV-2, a novel coronavirus capable of human infection and transmission, was found to be responsible.
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